45 research outputs found

    The Effects of Kids’ Cooking Camps on Native American Children’s Knowledge and Habits Related to Food Safety, Preparation, and Nutrition

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    A pilot research study was conducted to determine if cooking camps could increase knowledge and improve habits of Native American children related to food safety, nutrition, and reported food and exercise habits. Forty Native American youth were recruited for participation in one of four kids’ cooking camps. Each child took a pre-assessment upon their arrival at camp and a post-assessment on the last day of camp, as well as a pre- and post-test for each lesson. The children participated in lessons and food preparation activities during the six hours per day, four day camp. The thirty subjects taking both the pre- and post-assessment had significant increases in physical activity and food safety knowledge. Parents/guardians provided their input through focus groups and phone interviews. Parents reported their children increased consumption of fruits and vegetables after camp

    SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

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    BACKGROUND: Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving limited insights into mucosal defences that prevent viral replication and onward transmission. We studied nasal and plasma antibody responses one year after hospitalisation for COVID-19, including a period when SARS-CoV-2 vaccination was introduced. METHODS: In this follow up study, plasma and nasosorption samples were prospectively collected from 446 adults hospitalised for COVID-19 between February 2020 and March 2021 via the ISARIC4C and PHOSP-COVID consortia. IgA and IgG responses to NP and S of ancestral SARS-CoV-2, Delta and Omicron (BA.1) variants were measured by electrochemiluminescence and compared with plasma neutralisation data. FINDINGS: Strong and consistent nasal anti-NP and anti-S IgA responses were demonstrated, which remained elevated for nine months (p < 0.0001). Nasal and plasma anti-S IgG remained elevated for at least 12 months (p < 0.0001) with plasma neutralising titres that were raised against all variants compared to controls (p < 0.0001). Of 323 with complete data, 307 were vaccinated between 6 and 12 months; coinciding with rises in nasal and plasma IgA and IgG anti-S titres for all SARS-CoV-2 variants, although the change in nasal IgA was minimal (1.46-fold change after 10 months, p = 0.011) and the median remained below the positive threshold determined by pre-pandemic controls. Samples 12 months after admission showed no association between nasal IgA and plasma IgG anti-S responses (R = 0.05, p = 0.18), indicating that nasal IgA responses are distinct from those in plasma and minimally boosted by vaccination. INTERPRETATION: The decline in nasal IgA responses 9 months after infection and minimal impact of subsequent vaccination may explain the lack of long-lasting nasal defence against reinfection and the limited effects of vaccination on transmission. These findings highlight the need to develop vaccines that enhance nasal immunity. FUNDING: This study has been supported by ISARIC4C and PHOSP-COVID consortia. ISARIC4C is supported by grants from the National Institute for Health and Care Research and the Medical Research Council. Liverpool Experimental Cancer Medicine Centre provided infrastructure support for this research. The PHOSP-COVD study is jointly funded by UK Research and Innovation and National Institute of Health and Care Research. The funders were not involved in the study design, interpretation of data or the writing of this manuscript

    Reservoir quality of Cenozoic carbonate buildups and coral reef terraces

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    Almost half of SE Asia's considerable hydrocarbon reserves are contained in carbonates. The majority of these reservoirs are Miocene buildups up to tens of kilometres across. However, with the exception of a few fields, there is little detailed data on how local depositional and diagenetic conditions influence the considerable heterogeneities in reservoir quality often encountered. This study focuses on factors influencing the facies, diagenetic and reservoir variability of comparable Modern, Quaternary and Neogene reef associated deposits from the Tukang Besi Archipelago, Central Indonesia.The Archipelago includes large atolls, a number of smaller buildups and 4 main islands each with modern rimmed shelves or fringing reefs. On the islands, over ten late Neogene and Quaternary coral reef terraces have been uplifted to maximum heights of ~300 m. Analysis of the modern deposits allows initial reservoir potential to be assessed and related to local environmental conditions. The influence of diagenesis on final reservoir quality is evaluated for the depositional facies exposed in the uplifted terraces. The overall spatial distribution of effective porosity across the area is strongly dependent on local energy conditions, water depth, carbonate producers, size of atolls or islands, climate and local meteoric diagenetic processes. This evaluation of spatial variability in carbonate reservoir characteristics provides much needed analogue data as the hydrocarbon industry focuses on improving recovery from existing fields and exploring for new reserves

    'Voyaging in': colonialism and migration

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    A major reference chapter on the history of the literature of colonialism and migration 1945-70. The book marks an intervention into conventional histories of British Literature. The chapter illustrates and analyses the influential formation of alternative modernities by migrant writers resident in Britain during this period; it also extends the gaze to the period before 1945 earlier in the twentieth century. Maps new ways of reading literary history; broad and wideranging discussion of migration during this period

    The gender of modernity

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    ‘Speed, violence, women, America’: popular fictions

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    Theatre and drama between the wars

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    Surrealism in England

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    Biography and autobiography: 1918-45

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    Literary Criticism and Cultural Politics

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